LivaNova

6500 Wedgwood Road North

Maple Grove, MN 55311

763.220.4110

IMPORTANT SAFETY INFORMATION

Disclaimer: Individual results may vary. This information is designed to help you learn more about TMVR. It is intended to provide you with helpful information but, is for information purposes only, is not medical advice and should not be used as an alternative to speaking with your doctor. Be sure to discuss questions specific to your health and treatments with a healthcare professional. For more information, please speak to your healthcare professional. Limited by federal law to investigational use in the United States, Canada and Europe. Not for sale in United States, Canada or Europe. For use by clinical investigators only. Related information on the study can be found at www.clinicaltrials.gov using identifier NCT02768402. Trademarks may be registered and are the property of their respective owners. Copyright 2017 LivaNova, Inc. All rights reserved.

TREATMENT OPTIONS

WHAT ARE MY TREATMENT OPTIONS?

TRADITIONAL OPEN HEART SURGERY

Open-heart surgery has been the standard of care to replace a diseased mitral valve. During open-heart surgery, the chest is opened so the doctor can reach the heart, and repair the diseased valve or replace it with a new valve. Transcatheter Mitral Valve Replacement, or TMVR, is a new less invasive investigational approach to replacing the mitral valve in patients deemed high-risk for open-heart surgery.

Traditional

open heart surgery

AN INVESTIGATIONAL NEW APPROACH

Unlike traditional open-heart surgery, TMVR uses a tube (catheter) through an incision in the groin instead of opening the chest to replace the mitral valve. First, a metal structure called an Anchor, is inserted into the catheter, advanced into the heart and positioned into the opening of the damaged mitral valve. Once the Anchor is in place, the replacement Valve is inserted into the catheter and advanced into the heart. The doctor positions the replacement Valve into the Anchor, locking it in place, and removes the catheter.

Heart

Catheter

Left
atrium

Septum

Blood from lungs
flowing into
pulmonary veins

Prosthetic
mitral valve

Left
ventricle

Right
ventricle

Inferior
vena cava

Tricuspid valve

Right atrium

Superior
vena cava

Access to the heart is gained minimally invasively through the groin, which eliminates the need to open the chest

Mitral
valve

The catheter is advanced
to the mitral valve

Anchor

The Anchor is released
to the mitral valve

Prosthetic valve
(pre-deployment)

Finally, the Valve is connected
to the Anchor

LEARN MORE ABOUT THE PROCEDURE

Click below to watch the animation.